Neuromodulation / TMS
Neuromodulation refers to the process of altering or regulating nerve activity using electrical, magnetic, or chemical stimulation to modulate the nervous system’s function. Neuromodulation works by influencing the activity of neurons and neurotransmitter systems in targeted regions. It can inhibit or stimulate neurons to correct dysfunction or reduce symptoms of a disorder. It is a broad term used in medical treatments that target the central nervous system (brain and spinal cord) and the peripheral nervous system (nerves outside the brain and spinal cord), aiming to treat various neurological conditions and disorders.
Advantages:
- Targeted treatment: Neuromodulation can directly affect the specific part of the nervous system causing symptoms.
- Reversible and adjustable: In many cases, neuromodulation therapies can be fine-tuned or reversed if needed.
- Non-pharmacological option: It offers an alternative to medications, especially for patients who may not respond to drugs or experience side effects.
There are many types of neuro-modulation – both invasive and non-invasive:
- Electrical Stimulation:
- Devices like neurostimulators deliver controlled electrical pulses to specific nerves or brain regions. These pulses can alter abnormal neural activity, providing therapeutic effects.
- Deep Brain Stimulation (DBS) is an example of neuromodulation used to treat conditions like Parkinson’s disease, where electrodes are implanted in specific brain areas to control abnormal movements.
- Chemical Stimulation:
- Neuromodulation can also involve the release of drugs or neurotransmitters directly into specific areas of the nervous system to influence neural circuits and functions.
- Therapeutic Uses:
- Chronic pain: Devices like spinal cord stimulators are used to manage chronic pain by interrupting pain signals before they reach the brain.
- Movement disorders: DBS is widely used for Parkinson’s disease, essential tremor, and dystonia.
- Epilepsy: Vagus nerve stimulation (VNS) is used to reduce the frequency and severity of seizures in people with epilepsy.
- Depression: Some forms of neuromodulation, such as transcranial magnetic stimulation (TMS), are used for treatment-resistant depression.
- Bladder and bowel dysfunction: Sacral nerve stimulation can help regulate bladder and bowel function in conditions like overactive bladder or fecal incontinence.
- Types of Neuro-modulation:
- Spinal Cord Stimulation (SCS): Electrodes are placed near the spinal cord to manage pain signals.
- Deep Brain Stimulation (DBS): Electrodes are implanted in the brain to modulate neural activity in specific regions.
- Vagus Nerve Stimulation (VNS): A device is implanted to stimulate the vagus nerve, often used in epilepsy or depression.
- Transcranial Magnetic Stimulation (TMS): Repetitive Transcranial Magnetic Stimulation (rTMS or TMS) is a type of non-invasive neuromodulation where a magnetic field is used to stimulate nerve cells in the brain. For certain conditions, rTMS is FDA-Cleared. Magnetic e-Resonance Therapy (MeRT®) is a type of rTMS that also incorporates the use of an Electroencephalogram. In most cases, MeRT® is being used “off-label.”
What is MeRT and How does MeRT works?
MeRT stands for Magnetic e-Resonance Therapy, a therapy that is used to treat Autism, Depression, PTSD, TBI, and a wide range of other issues that stem from brain activity imbalances. Dr. Winfrey uses gentle magnetic stimulation to enhance neurological development and help the brain to heal and open pathways.
MeRT treatment starts with an evaluation that uses sophisticated brain imaging to locate the areas of the brain that are not communicating. Then we create a customized treatment of gentle magnetic waves specifically for your brain patterns. We stimulate those parts of the brain and encourage them to start communicating again. The treatment uses no drugs or medications and is completely non-invasive. And, in some instances, results have been astonishing.
An Overview of MeRT Treatment
Gentle magnetic waves stimulate areas of the brain that are not communicating well with a targeted frequency specifically based on your needs. MeRT, or Magnetic e-Resonance Therapy, is a breakthrough technology that empowers doctors to analyze your brainwave data and provide targeted treatment to give you the best possible outcome. The magnetic waves used are tailored to exact parts of your brain and exact frequencies that help your brain open up areas that need support.
How does MeRT do this, exactly? Well, it starts with how the brain works.
Your brain is composed of approximately 100 billion neurons. These neurons interact with each other through brain waves, or tiny electrical oscillations, to control how your brain functions.
Your neurons can be disrupted by internal or external forces, causing brain dysfunction. Some of these forces can include:
- Trauma to the head such as a concussion
- Post-traumatic stress disorder
- Major Depressive Disorder
- Developmental disorders such as Autism, ADD, and ADHD
- Illness or disease such as stroke or Parkinson’s Disease
- Drug or alcohol addiction
- Learning disorders
- Dementia
- Multiple sports injuries (head hits)
- Anxiety
- Sleeping disorders
- Congenital issues
These disruptions can be minor or significant. Everyone has different levels of tolerance. Some people still function in day-to-day activities, while others are to some degree debilitated and lose their quality of life. MeRT attempts to reprogram these abnormal electrical signals in the brain. By identifying where your brain waves are not properly communicating, we can help to restore optimal function. MeRT technology can reshape the activity in your brain, regardless of what caused the dysfunction. Patients have reported results that they consider nothing short of miraculous.
*** Results are based on active and strict observation of our regimens. Results may vary based on the individual user and are not guaranteed.***
The 3 Components of MeRT
MeRT, or Magnetic e-Resonance Therapy, uses a three-part protocol that measures, analyzes, and improves brain function. The three part are:
qEEG
(quantitative electroencephalogram)
This non-invasive test is also called “brain mapping”. We simply place a cap on your head to map your unique brainwaves.
EKG/ECG
(electrocardiogram)
While performing the qEEG, we also use an EKG to measure your heart’s electrical signals. This provides the ,most accurate results possible.
rTMS
(repetitive transcranial magnetic stimulation)
After analyzing your results and developing your tailored program, we place magnetic coils along your scalp to stimulate targeted brain areas.
Testing
Your first appointment will consist of two simple tests, a qEEG and an EKG. These tests are easy, painless, and performed right in our office. For the EEG, we place a cap on your head to measure the electrical activity in your brain and map out any areas not performing as they should. We also perform an EKG to record your heart’s electrical signals. Once we perform these tests, our team will carefully analyze the results. Based on this analysis, we develop a treatment plan customized to your specific condition and schedule your assessment period of treatment.
Consultation
After your tests are complete and we’ve reviewed and analyzed them, you will have a one-on-one consultation with Dr. Winfrey. This can be done virtually from the comfort of your home. We will discuss your test results and treatment protocols, answer any remaining questions, and let you know more about what to expect during your assessment period.
Assessment Period
Questionnaires and Intake forms
List of Studies
Neuromodulation & EEG Relevance
- The Quantitative Electroencephalogram and the Low-Resolution Electrical Tomographic Analysis in Posttraumatic Stress Disorder
- Traumatic Brain Injury – An EEG Point of View
- Repetitive Transcranial Magnetic Stimulation Affects Behavior by Biasing Endogenous Cortical Oscillations
- Rhythmic TMS Causes Local Entrainment of Natural Oscillatory Signatures
- Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury
- The Physiological Basis of Transcranial Magnetic Stimulation
- Applications of Transcranial Magnetic Stimulation (TMS) in Child and Adolescent Psychiatry
Autism Spectrum Disorder
- A systematic review of transcranial magnetic stimulation treatment for autism spectrum disorder
- A Stable Pattern of EEG Spectral Coherence Distinguishes Children with Autism from Neuro-Typical Controls – A Large Case Control Study
- Effects of Repetitive Transcranial Magnetic Stimulation on Children with Low‐Function Autism
- “EEG Analytics for Early Detection of Autism Spectrum Disorder: A Data-driven Approach”
- “Improved Autism Behaviors After Non-invasive Cerebral Trans-magnetic Stimulation Using Customized Frequency Modulation: Follow-up”
- Outcomes from Individual Alpha Frequency Guided Repetitive Transcranial Magnetic Stimulation in Children with Autism Spectrum Disorder – A Retrospective Chart Review
- “The Potential of Magnetic Resonant Therapy in Children with Autism Spectrum Disorder”
- Noninvasive EEG-EKG Guided Trans-Magnetic Stimulation at Natural Resonance Frequency in Children with Autism: Randomized Double-Blinded Pilot Study
- Resting State Cortical Connectivity Reflected in EEG Coherence in Individuals with Autism
- Resting State EEG Abnormalities in Autism Spectrum Disorder
- EEG Complexity as a Biomarker for Autism Spectrum Disorder Risk
- Treatment of Executive Function Deficits in Autism Spectrum Disorder with Repetitive Transcranial Magnetic Stimulation: A Double-Blind, Sham-Controlled, Pilot Trial
- Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Event-Related Potential (ERP) Indices of Attention in Autism
- Effects of Weekly Low-Frequency rTMS on Autonomic Measures in Children with Autism Spectrum Disorder
- TMS Shows Promise as Treatment for Adults with Both Depression and Autism
- A Double-Blind, Randomized Trial of Deep Repetitive Transcranial Magnetic Stimulation (rTMS) for Autism Spectrum Disorder
- The Potential of Repetitive Transcranial Magnetic Stimulation for ASD: A Consensus Statement
- Use of Transcranial Magnetic Stimulation in Autism Spectrum Disorders
PTSD
- “Magnetic Resonance Therapy Improve Clinical Phenotype and EEG Alpha Power in Post-traumatic Stress Disorder”
- Individualized Electromagnetic Treatment in Posttraumatic Stress Disorder: a Randomized, Double-blind, Sham-controlled Trial
- Fronto-Central Resting-State 15-29 Hz Transient Beta Events Change with Therapeutic Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder and Major Depressive Disorder
- “Magnetic E-Resonant Therapy Alleviates Combat Related Post-traumatic Stress Disorder,” in Aerospace Medical Association, March 2017
- EEG/EKG Guided TMS in Veterans with PTSD Randomized Double-Blinded Pilot Study
- Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in Posttraumatic Stress Disorder: a Double-Blind, Placebo-Controlled Study
- The Quantitative Electroencephalogram and the Low-Resolution Electrical Tomographic Analysis in Posttraumatic Stress Disorder
- Frontiers | A retrospective chart review to assess the impact of alpha-guided transcranial magnetic stimulation on symptoms of PTSD and depression in active-duty special operations service members (frontiersin.org)
Major Depression
- TMS Should Be Considered as First-Line Treatment for Moderate to Severe Major Depressive Disorder
- The Relationship Between Brain Oscillatory Activity and Therapeutic Effectiveness of Transcranial Magnetic Stimulation in the Treatment of Major Depressive Disorder
- Transcranial Magnetic Stimulation (TMS) for Major Depression: A Multisite, Naturalistic, Observational Study of Acute Treatment Outcomes in Clinical Practice
- A Pilot Study of the use of EEG-Based Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression
- Accelerated TMS for Depression: A Systematic Review and Meta-Analysis
- Transcranial Magnetic Stimulation for the Treatment of Major Depression
- The Expanding Evidence Base for rTMS Treatment of Depression
Anxiety
- Electroencephalogram Abnormalities in Panic Disorder Patients: A Study of Symptom Characteristics and Pathology
- EEG Correlates of Different Types of Anxiety in 14 – to 15-Year-Old Teenagers
- Transcranial Magnetic Stimulation in Anxiety and Trauma-Related Disorders: A Systematic Review and Meta-Analysis
- Repetitive Transcranial Magnetic Stimulation for Generalized Anxiety Disorder: A Systematic Literature Review and Meta-Analysis
- A Case Study: The Effect of Transcranial Magnetic Stimulation (TMS) on Stress Levels, Quality of Sleep, and the Autonomic Nervous System
TBI/Concussion
- Magnetic Resonance Therapy for Non-invasive Neuromodulation of Minimally Conscious State – A Report of 2 Cases
- Transcranial Magnetic Stimulation Facilitates Neurorehabilitation After Pediatric Traumatic Brain Injury
- A Pilot Randomised Double-Blind Study of the Tolerability and Efficacy of Repetitive Transcranial Magnetic Stimulation on Persistent Post-Concussion Syndrome
- Repetitive Transcranial Magnetic Stimulation for Treatment of Depression in a Patient With Severe Traumatic Brain Injury
- The Use of Repetitive Transcranial Magnetic Stimulation (rTMS) following Traumatic Brain Injury (TBI): A Scoping Review
- TBI During a Course of TMS: A Case Report
ADHD
- Adult-ADHD and Potential Role of Transcranial Magnetic Stimulation (TMS & RTMS) Investigation & Treatment
- Repetitive Transcranial Magnetic Stimulation (rTMS): New Tool, New Therapy and New Hope for ADHD
- The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression – PMC (nih.gov)
OCD
- Real-World Efficacy of Deep TMS for Obsessive-Compulsive Disorder: Post-marketing data collected from twenty-two clinical sites
- Transcranial Magnetic Stimulation in the Treatment of Obsessive–Compulsive Disorder: Current Perspectives
- Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Prospective Multicenter Randomized Double-Blind Placebo-Controlled Trial
Migraines
- Transcranial Magnetic Simulation in the Treatment of Migraine
- Transcranial Magnetic Stimulation for Migraine – Clinical Effects
- The Efficacy of Transcranial Magnetic Stimulation on Migraine: A Meta-Analysis of Randomized Controlled Trials
Long Covid Brain Fog
- Effect of Repetitive Transcranial Magnetic Stimulation on Long Coronavirus Disease 2019 with Fatigue and Cognitive Dysfunction
- Real World Research on Transcranial Magnetic Stimulation Treatment Strategies for Neuropsychiatric Symptoms with Long-COVID in Japan
- Intracortical GABAergic Dysfunction in Patients with Fatigue and Dysexecutive Syndrome After COVID-19
- The Restoration After Repetitive Transcranial Magnetic Stimulation Treatment on Cognitive Ability of Vascular Dementia Rats and Its Impacts on Synaptic Plasticity in Hippocampal CA1 Area
Alzheimer’s
- Transcranial Magnetic Stimulation Treatment in Alzheimer’s Disease: A Meta-Analysis of its Efficacy as a Function of Protocol Characteristics and Degree of Personalization
- Transcranial Magnetic Stimulation as a Diagnostic and Therapeutic Tool in Various Types of Dementia
- Repetitive Transcranial Magnetic Stimulation for the Treatment of Cognitive Impairment in Frontotemporal Dementia: An Open-Label Pilot Study
- The Therapeutic Efficacy of Transcranial Magnetic Stimulation in Managing Alzheimer’s Disease: A Systemic Review and Meta-Analysis
Pain
- Transcutaneous Magnetic Stimulation (tMS) in Alleviating Post-Traumatic Peripheral Neuropathic Pain States: A Case Series
- Effect of Repetitive Transcranial Magnetic Stimulation on Pain Management: A Systematic Narrative Review
- Noninvasive Transcranial Magnetic Stimulation (TMS) in Chronic Refractory Pain: A Systematic Review
SUD/Smoking Cessation
- Effect of High-Frequency Transcranial MagneticStimulation on Craving in Substance Use Disorder:A Meta-Analysis
- Can Deep Transcranial Magnetic Stimulation (DTMS) Be Used to Treat Substance Use Disorders (SUD)? A Systematic Review
- Modulating Neural Circuits with Transcranial Magnetic Stimulation: Implications for Addiction Treatment Development
- Repetitive Transcranial Magnetic Stimulation for Smoking Cessation: A Pivotal Multicenter Double‐Blind Randomized Controlled Trial
- Smoking Cessation With 20 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Applied to Two Brain Regions: A Pilot Study
- Transcranial Magnetic Stimulation Treatment for Smoking Cessation: An Introduction for Primary Care Clinicians
MeRT® Ongoing Clinical Trials with Department of Defense for PTSD, Post-Concussion Disorders, TBI
- Clinical Trial to Evaluate the Safety and Efficacy of MeRT® Treatment in Post-Traumatic Stress Disorder
- To Evaluate the Efficacy of EEG-guided Magnetic Resonant Therapy in War Veterans With Posttraumatic Stress Disorder
- sTMS for Substance Use-disordered Veterans
- Congressional Approval – No Hero Left Untreated Act